(ED12) Gut microbes and health: from molecular to metabolic impact
Wednesday 31 March & Thursday 1 April 2010
Organizers: Glenn Gibson email g.r.gibson@reading.ac.uk, Michael Ginger, Lucinda Hall & Cath Rees |
The past decade has seen major advances in our understanding of the interactions between gut microbiota and the host. The use of molecular technologies have helped to reliably determine microbial type in this highly complex microbial ecosystem and also provided tools to assess probiotic and prebiotic functionality in vitro and in vivo. Many new products directed towards gut flora interaction have arisen and our understanding of health aspects of these has progressed quickly. With the application of high throughput biochemical approaches to gut microbial interactions, there is increasing knowledge on the metabolic impact of the microbiota. It is apparent that disorders within and outside of the gut can be affected by activities of the indigenous microflora. This symposium will summarise the latest findings in the area and explore new avenues of research. Session outline » Posters »
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| Provisional Programme |
| Wednesday 31 March 2010 |
| Chair: Glenn R. Gibson (University of Reading) |
| 0900 |
James Versalovic |
Texas Children's Hospital, USA |
The Human Microbiome project |
| 0930 |
Elaine Holmes |
Imperial College London |
Application of metabonomics to gut microbial interactions |
| 1000 |
Refreshments |
| 1030 |
Michael Blaut |
German Institute of Human Nutrition, Germany |
Simplified models for mechanistic studies on host-microbe interactions |
| 1100 |
George T. Macfarlane |
University of Dundee |
Fermentation processes in the large intestine, and their metabolic impact on the host |
| 1200 |
Marjory Stephenson Prize Lecture
Prof Dr Jan Tommassen (Utrecht University, The Netherlands) Assembly of outer membrane proteins in bacteria and mitochondria |
| 1300 |
Lunch |
| Chair: Michael L. Ginger (University of Lancaster) |
| 1400 |
John Samuelson |
Boston University, USA |
Protozoan parasites and host-pathogen interactions |
| 1430 |
Anna Szczepańska et al |
Rowett Institute of Nutrition & Health, Aberdeen |
Offered paper: Functional screening of a genomic library from a human gut anaerobe in Escherichia coli and Lactococcus lactis using a novel shuttle vector
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| 1445 |
Laura E.J. Searle et al |
Veterinary Laboratories Agency, Weybridge |
Offered paper: Galactooligosaccharide: a prebiotic demonstrating efficacy at reducing Salmonella Typhimurium invasion in vitro and in vivo
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| 1500 |
Karen P. Scott et al |
Rowett Institute of Nutrition & Health, Aberdeen |
Offered paper: Response of human gut obligately anaerobic commensal bacteria to inulin and FOS
|
| 1515 |
F. Jeffers et al |
Institute of Food Research, Norwich |
Offered paper: How do gut microbes bind to mucus? |
| 1530 |
Refreshments |
| 1600 |
Stephanie Schüller et al |
University College London Medical School |
Offered paper: Microaerobic conditions enhance type III secretion and adherence of enterohaemorrhagic Escherichia coli to polarized human intestinal epithelial cells |
| 1615 |
M. Baran et al |
University of Reading |
Offered paper: Cytokine production by peripheral blood mononuclear cells (PBMCs) stimulated by Bifidobacteria spp. or galactooligosaccharide |
| 1630 |
Willem de Vos |
Wageningen and Helsinki University, The Netherlands |
Genomes and gut: what do we know now? |
| 1700 |
End of session |
| 1730 |
Poster-viewing session |
| Thursday 1 April 2010 |
| Chair: Lucinda Hall (Barts & The London) |
| 0900 |
Bob A. Rastall |
University of Reading |
Prebiotic oligosaccharides for gut health |
| 0930 |
Kieran Tuohy |
University of Reading |
Diet, gut microbiota and ageing |
| 1000 |
Refreshments |
| 1030 |
Simon M. Cutting |
University of London, Egham |
Application of GI interventions and gut diseases (UC, CD, IBS, CRC) |
| 1100 |
Daniel Poulain |
Centre Hospitalier Régional Universitaire de Lille, France |
Yeast cell wall antigens and Crohn's disease |
| 1130 |
Nathalie Delzenne |
Université Catholique de Louvain, Belgium |
The gut microbiota as a target in the management of obesity and associated diseases |
| 1200 |
End of symposium / Lunch |