Spring 2010 Meeting: Edinburgh International Conference Centre, Edinburgh - 29 March - 1 April 2010

(ED12) Gut microbes and health: from molecular to metabolic impact
Wednesday 31 March & Thursday 1 April 2010
Organizers: Glenn Gibson — email g.r.gibson@reading.ac.uk, Michael Ginger, Lucinda Hall & Cath Rees
The past decade has seen major advances in our understanding of the interactions between gut microbiota and the host. The use of molecular technologies have helped to reliably determine microbial type in this highly complex microbial ecosystem and also provided tools to assess probiotic and prebiotic functionality in vitro and in vivo. Many new products directed towards gut flora interaction have arisen and our understanding of health aspects of these has progressed quickly. With the application of high throughput biochemical approaches to gut microbial interactions, there is increasing knowledge on the metabolic impact of the microbiota. It is apparent that disorders within and outside of the gut can be affected by activities of the indigenous microflora. This symposium will summarise the latest findings in the area and explore new avenues of research.

Session outline  PDF»
Posters »

Provisional Programme
Wednesday 31 March 2010
Chair: Glenn R. Gibson (University of Reading)
0900 James Versalovic Texas Children's Hospital, USA The Human Microbiome project
0930 Elaine Holmes Imperial College London Application of metabonomics to gut microbial interactions
1000 Refreshments
1030 Michael Blaut German Institute of Human Nutrition, Germany Simplified models for mechanistic studies on host-microbe interactions
1100 George T. Macfarlane University of Dundee Fermentation processes in the large intestine, and their metabolic impact on the host
1200 Marjory Stephenson Prize Lecture
Prof Dr Jan Tommassen (Utrecht University, The Netherlands)
Assembly of outer membrane proteins in bacteria and mitochondria
1300 Lunch
Chair: Michael L. Ginger (University of Lancaster)
1400 John Samuelson Boston University, USA Protozoan parasites and host-pathogen interactions
1430 Anna Szczepańska et al Rowett Institute of Nutrition & Health, Aberdeen Offered paper: Functional screening of a genomic library from a human gut anaerobe in Escherichia coli and Lactococcus lactis using a novel shuttle vector ()
1445 Laura E.J. Searle et al Veterinary Laboratories Agency, Weybridge Offered paper: Galactooligosaccharide: a prebiotic demonstrating efficacy at reducing Salmonella Typhimurium invasion in vitro and in vivo
1500 Karen P. Scott et al Rowett Institute of Nutrition & Health, Aberdeen Offered paper: Response of human gut obligately anaerobic commensal bacteria to inulin and FOS
1515 F. Jeffers et al Institute of Food Research, Norwich Offered paper: How do gut microbes bind to mucus?
1530 Refreshments
1600 Stephanie Schüller et al University College London Medical School Offered paper: Microaerobic conditions enhance type III secretion and adherence of enterohaemorrhagic Escherichia coli to polarized human intestinal epithelial cells
1615 M. Baran et al University of Reading Offered paper: Cytokine production by peripheral blood mononuclear cells (PBMCs) stimulated by Bifidobacteria spp. or galactooligosaccharide
1630 Willem de Vos Wageningen and Helsinki University, The Netherlands Genomes and gut: what do we know now?
1700 End of session
1730 Poster-viewing session
Thursday 1 April 2010
Chair: Lucinda Hall (Barts & The London)
0900 Bob A. Rastall University of Reading Prebiotic oligosaccharides for gut health
0930 Kieran Tuohy University of Reading Diet, gut microbiota and ageing
1000 Refreshments
1030 Simon M. Cutting University of London, Egham Application of GI interventions and gut diseases (UC, CD, IBS, CRC)
1100 Daniel Poulain Centre Hospitalier Régional Universitaire de Lille, France Yeast cell wall antigens and Crohn's disease
1130 Nathalie Delzenne Université Catholique de Louvain, Belgium The gut microbiota as a target in the management of obesity and associated diseases
1200 End of symposium / Lunch

Last updated 12 February 2010