(ED01) The 'omics revolution: elucidating the pathways of virus infection
Monday 29 & Tuesday 30 March 2010
Organizers: Adrian Whitehouse — email a.whitehouse@leeds.ac.uk & Paul Kellam
2010 marks the ten year anniversary of the release of the draft human genome. In that time the power of different methods for investigating host and virus interaction have increased beyond imagination. This symposium brings together international leaders in all aspects of genome scale virology, from the use if next generation sequence methods to discover new viruses to the structural biology of the virus universe. The symposium will address how we use these data to understand virus evolution, host-virus interactions and the genetics of host susceptibility to infection.
Session outline  »
|
| Provisional Programme |
| Monday 29 March 2010 |
| Chairs: Adrian Whitehouse & Paul Kellam |
| 0900 |
W. Ian Lipkin |
Columbia University, New York, USA |
Microbe hunting in the 21st Century |
| 0945 |
Derek J. Smith |
University of Cambridge |
The evolution of influenza viruses |
| 1030 |
Refreshments |
| 1100 |
Arnie J. Berk |
University of California at Los Angeles, USA |
e1a reverses cellular differentiation and induces S-phase by globally re-localizing RB/CBP complexes on chromatin
|
| 1145 |
End of morning session |
| 1200 |
SGM PRIZE MEDAL LECTURE
Professor Sir Paul Nurse (President, Rockefeller University, USA)
Controlling the cell cycle
|
| 1300 |
Lunch |
| Chair: Mark Harris (University of Leeds) |
| 1400 |
Bryan R. Cullen |
Duke University, North Carolina, USA |
Viruses, microRNAs and RNA interference |
1445: Offered paper
MicroRNA199/214 function in murine and human cytomegalovirus infection: lessons from agonist-antagonist genome-wide screening
Amy Buck et al (University of Edinburgh)
1500: Offered paper
Studying host-virus interactions by chemical genetics
Ariberto Fassati et al (University College London)
1515: Offered paper
The effect of hepatitis C virus infection on host gene expression
Samantha Blackham et al (Imperial College London)
1530: Refreshments
Chair: Steve Goodbourn (St George's Hospital Medical School)
1600: Hayes-Burnet Travel Award Winner
Pathogenic consequences of H5N1 polymerase changes in the mammalian host
J. Butler et al (1CSIRO Livestock Industries & University of Melbourne)
1615: Offered paper
Enhanced hepatitis C genome replication and lipid accumulation mediated by inhibition of AMP-activated protein kinase in hepatitis C virus infected cells
Jamel Mankouri et al (University of Leeds)
1630: Offered paper
Computational analysis of the complete rotavirus genome database together with selective biochemical probing reveals highly conserved RNA structures with potential cis-acting functions
Wilson Li et al (University of Cambridge)
1645: Offered paper
Reprogramming the host environment during Epstein-Barr virus replication
Alison J. Sinclair et al (University of Sussex)
17.00: Offered paper
Transcriptome analysis of EBNA3B-knockout LCLs identifies potentially oncogenic transcripts regulated by EBV
Rob White et al (Imperial College London)
1715: End of session
1730: Poster-viewing session
|
| Tuesday 30 March 2010 |
| Chairs: Adrian Whitehouse & Paul Kellam |
| 0830 |
Micheal Katze |
University of Washington, USA |
How can we save the world from the next pandemic-can systems and computational biology be more effective than 50 years of traditional virology?
|
| 0910 |
Jürgen Haas |
University of Edinburgh |
A systematic analysis of virus-host protein interactions in herpesviruses |
| 0950 |
Dennis H. Bamford |
University of Helsinki, Finland |
Organization of the viral universe - structure leads the way |
| 1030 |
Refreshments |
| 1100 |
David A. Matthews |
University of Bristol |
High throughput proteomic analysis of the adenovirus infected nucleolus |
| 1200 |
Fleming Prize Lecture
Dr Steve Diggle (University of Nottingham)
Microbial communication and virulence: lessons from evolutionary theory |
| 1300 |
Lunch |
| Chair: David Blackbourn |
| 1400 |
Susan S. Ross |
University of Pennsylvania, Philadelphia, USA |
Using genetics to study host-virus interactions |
1445: Offered paper
Transcriptome analysis of the effects of Varicella-Zoster virus infection in an epidermal differentiation model
Inga Dry et al (University College London)
1500: Offered paper
In vivo gene expression analysis in non-human primates infected with attenuated or wild-type measles virus
M. Ludlow et al (Erasmus MC, The Netherlands)
1515: Offered paper
Characterisation of fowlpox interferon resistance proteins
S.M. Laidlaw et al (Imperial College London)
1530: Refreshments
Chair: Andrew Lever (University of Cambridge)
1600: Offered paper
The Murine norovirus ORF4 is a novel virulence determinant
Ian Goodfellow et al (Imperial College London)
1615: Offered paper
The molecular basis of hepatitis C virus (HCV) resistance to rimantadine
Elizabeth Atkins et al (University of Leeds)
1630: Offered paper
Deregulation of inflammatory and anti-viral signalling by the Adenoviral E3-14.7K immunomodulatory protein
Andrew Macdonald et al (University of Leeds)
1645: Offered paper
Transport pathways utilized to travel into and out of the nucleus in herpes simplex virus-infected cells
Poonam Malik et al (University of Edinburgh)
1700: Offered paper
Cellular tropism of the infectious bronchitis virus (IBV) S glycoprotein
Erica Bickerton et al (Institute for Animal Health)
|
| 1715 |
End of symposium |
| 1730 |
Poster-viewing session |
