Journal of General Virology

Fig. 2. Functional RNA–protein interactions in the FMDV and HCV IRES elements. (A) FMDV interactions. PTB-binding sites are taken from Luz & Beck (1991) and Kolupaeva et al. (1996). The interaction sites of eIF4G and eIF4B are taken from López de Quinto & Martínez-Salas (2000). Thick lines correspond to regions essential for IRES activity (Luz & Beck, 1991; Martínez-Salas et al., 1996; López de Quinto & Martínez-Salas, 1997, 2000). (B) HCV interactions. Binding sites of eIF3 and the 40S ribosome subunit are described in Buratti et al. (1998), Sizova et al. (1998) and Kolupaeva et al. (2000).

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