Journal of General Virology

Fig. 3. Relationship between BDV laboratory strains and selected viruses reported to originate from human blood or brain tissue. A rooted phylogenetic consensus tree was generated by the neighbour-joining method using nucleotide sequences derived from regions encoding BDV protein p24 (nucleotides 1482–1814). The exception was isolate BDVHuP2br, for which sequence information was restricted to a fragment comprising nucleotides 1573–1772 (Nakamura et al., 2000). The tree was constructed using the software package Clustal-X. Bootstrap analysis was applied using 100 values. Viral sequences from human tissues reported by laboratories frequently working with laboratory strains V, He/80, rat BDV or MDCK-BDV are marked with red, green, orange and blue colour codes, respectively. Individual sequences are identified by their accession numbers. Sequences reported by Iwata et al. (1998) are marked by asterisks.

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